Doxorubicin-eluting bead vs conventional transcatheter arterial chemoembolization for hepatocellular carcinoma before liver transplantation

Table 2 Analysis of the treated nodules according to the type of transcatheter arterial chemoembolization (per nodule analysis) n (%)

Variable	All treated nodules 63 in 38 patients	Type of TACE		P value
		DEB-TACE 38 in 22 patients	c-TACE 25 in 16 patients
Degree of necrosis	54.3% ± 41.2%	55.7% ± 41.9%	52.2% ± 40.9%	0.7420
Complete necrosis (100%)	21 (33.3)	14 (36.8)	7 (28.0)	0.5877
Histological response				0.2834
Appropriate (necrosis ≥ 90%)	25 (39.7)	17 (44.7)	8 (32.0)
Partial (50% < necrosis < 90%)	9 (14.3)	3 (7.9)	6 (24.0)
Inadequate (necrosis ≤ 50%)	29 (46.0)	18 (47.4)	11 (44.0)
Diameters of nodules (cm)	2 (0.7-10)	1.8 (0.7-4.5)	2.2 (1-10)	0.1752
Number of nodules				0.2492
Single	17 (27.0)	8 (21.1)	9 (36.0)
Degree of necrosis	63.1% ± 37.8%	69.7% ± 34.8%	57.2% ± 41.5%	0.5144
Multiple	46 (73.0)	30 (78.9)	16 (64.0)
Degree of necrosis	51.1% ± 42.3%	52.0% ± 43.4%	49.4% ± 41.7%	0.8454
Modality of TACE				0.3015
Superselective	34 (54.0)	23 (60.5)	11 (44.0)
Degree of necrosis	73.9% ± 34.3%	76.2% ± 33.8%	69.1% ± 36.5%	0.5803
Non-superselective	29 (46.0)	15 (39.5%)	14 (56.0)
Degree of necrosis	31.3% ± 37.0%	24.3% ± 33.3%	38.9% ± 40.5%	0.2970

Analysis performed considering nodules reached by transarterial treatment (targeted lesions). Continuous variables are reported as median and range or mean and standard deviation and compared using the Student’s t test or Mann-Whitney U test as appropriate. TACE: Transcatheter arterial chemoembolization; DEB: Doxorubicin-eluting bead; c-TACE: Conventional TACE.