MicroRNA-21 as a potential colon and rectal cancer biomarker

doi:10.3748/wjg.v19.i34.5615

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Sep 14, 2013 (publication date) through Jul 20, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 14, 2013; 19(34): 5615-5621
Published online Sep 14, 2013. doi: 10.3748/wjg.v19.i34.5615

Table 1 Current screening methods and guidelines for colorectal cancer

Method	Sensitivity	Interval	Society
Fecal tests
FOBT		Yearly	USPSTF, ASGE,
			USMSTF
FIT	65.8%[32,33]	Yearly
Fecal DNA	50%-60%[34]	Unspecified	USMSTF
Serum markers
CEA	30%[35]
CA19-9
Imaging tests
DCBE	85%-97%[36]	Every 5 years	USMSTF
CTC	55%-94%[37]	Every 5 years	USMSTF
Optical tests
FS		Every 5 years	USPSTF, ASGE, USMSTF
		Every 10 years
FC			USPSTF, ASGE, USMSTF

FOBT: Fecal occult blood test; FIT: Fecal immunochemical based stool tests; CEA: Carcinoembryonic antigen; DCBE: Double-contrast barium enema; CTC: Computed tomography colonography; FS: Flexible sigmoidoscopy; FC: Flexible colonoscopy; USPSTF: United States Preventive Services Task Force; ASGE: American Society for Gastrointestinal Endoscopy; USMSTF: Multi-Society Task Force on Colorectal Cancer.

Citation: Li T, Leong MH, Harms B, Kennedy G, Chen L. MicroRNA-21 as a potential colon and rectal cancer biomarker. World J Gastroenterol 2013; 19(34): 5615-5621
URL: https://www.wjgnet.com/1007-9327/full/v19/i34/5615.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i34.5615