Propofol induces apoptosis and increases gemcitabine sensitivity in pancreatic cancer cells in vitro by inhibition of nuclear factor-κB activity

Figure 3 Cell viability by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay of pancreatic cancer MIA-PaCa-2 cells after propofol pretreatment. MIA-PaCa-2 cells pretreated with propofol (50 μmol/mL) for 24 h followed by coincubation with gemcitabine (10, 25, 50 and 100 μmol/L) for 72 h were analyzed for viable cells by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide. Viable cells were evaluated relative to gemcitabine-treated controls and interpreted as % viable cells. Data are averages of four to five independent experiments. ^aP < 0.05 vs control group.