Hypermethylation of TGF-&beta;1 gene promoter in gastric cancer

doi:10.3748/wjg.v19.i33.5557

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Sep 7, 2013 (publication date) through Nov 2, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 7, 2013; 19(33): 5557-5564
Published online Sep 7, 2013. doi: 10.3748/wjg.v19.i33.5557

Table 2 Impact of Helicobacter pylori on the frequency of transforming growth factor-β1 methylation in gastric tissues

	TGF-β1 methylation in GC patients		TGF-β1 methylation in Non-GC patients	Total¹
	Tumor	Non-tumor	Normal gastric mucosa
H. pylori (+)	21/38 (55.3%)	12/38 (31.6%)	8/22 (36.4%)	Total¹	41/98 (41.8%)
H. pylori (-)	3/9 (33%)	3/9 (33%)	3/17 (17.6%)	9/35 (25.7%)

¹Combined tumor and non-tumor tissue. GC: Gastric cancer; TGF-β1: Transforming growth factor-β1; H. pylori: Helicobacter pylori.

Citation: Wang YQ, Li YM, Li X, Liu T, Liu XK, Zhang JQ, Guo JW, Guo LY, Qiao L. Hypermethylation of TGF-β1 gene promoter in gastric cancer. World J Gastroenterol 2013; 19(33): 5557-5564
URL: https://www.wjgnet.com/1007-9327/full/v19/i33/5557.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i33.5557