Current status in the treatment options for esophageal achalasia

Table 3 Summary of the cumulative efficacies and complications of current treatment options of achalasia

	PD	Surgical myotomy	BTI	POEM
No. of studies	12	12	9	11
No. of patients	1097	1860	315	210
Excellent/good symptom response (range)	28%-92.9%	77%-97.2%	At 1 mo: 79% (64%-93%) At 1 yr: 41% (10%-55%)	82%-100%
Follow up (yr)	0.5-15	2.6-10.9	18 (6-30)	0.1-1
Major complications (range)	1%-2% Perforation	3%-34% Acid reflux	-	0.03% Acid reflux

PD: Pneumatic dilations; BTI: Botulinium toxin injection; POEM: Peroral endoscopic myotomy.