Editorial
Copyright ©2013 Baishideng Publishing Group Co.
World J Gastroenterol. Sep 7, 2013; 19(33): 5395-5401
Published online Sep 7, 2013. doi: 10.3748/wjg.v19.i33.5395
Table 1 Single nucleotide polymorphisms within human leukocyte antigen loci associated with outcomes of hepatitis B virus infection
Ethnic groupOutcomeHLA locusSNPOdds95%CIHLA haplotypeOddsRef.
JapaneseChronic infectionHLA-DPA1rs30770.560.51-0.61[7]
HLA-DPB1rs92775350.570.52-0.62
DPA1*0202-DPB1*05011.45
DPA1*0202-DPB1*03012.31
DPA1*0103-DPB1*04020.52
DPA1*0103-DPB1*04010.57
JapaneseChronic infectionHLA-DQrs28567181.431.33-1.54[8]
rs74539201.661.49-1.85
DQA1*0102-DQB1*030319.3
DQA1*0301-DQB1*06015.02
DQA1*0102-DQB1*06040.16
DQA1*0101-DQB1*05010.39
ChineseChronic infectionHLA-DPA1rs23953090.710.59-0.86[9]
HLA-DPA1rs30770.640.53-0.78
HLA-DPA1rs23012200.670.56-0.81
HLA-DPA1rs92773411.771.39-2.25
HLA-DPB1rs31350210.780.64-0.94
HLA-DPB1rs92775350.560.47-0.68
HLA-DPB1rs104845691.601.33-1.93
HLA-DPB1rs31289171.911.59-2.30
HLA-DPB1rs22813881.661.38-2.01
HLA-DPB1rs31172220.510.42-0.61
HLA-DPB1rs93803430.610.50-0.73
IndonesianVaccine responseHLA-DRrs31353631.591.45-1.73[10]
HLA-DPB1rs92775350.820.71-0.96
HLA-IIIrs92676652.131.82-2.49
ChineseHCCHLA-DQA1/DRB1rs92721051.281.22-1.35[11]
GRIK1*rs4558040.840.80-0.89
Japanese, KoreanChronic infectionHLA-DPA1rs30770.460.39-0.54[12]
HLA-DPB1rs92775420.500.43-0.60
ChineseChronic infectionHLA-DPB1rs92775350.600.51-0.70[13]
HLA-DPA1rs30770.810.75-0.95
HLA-DQrs74539200.600.49-0.73
HLA-DQrs28567180.750.64-0.89
HCCHLA-DQrs28567180.700.59-0.83
HLA-DPA1rs30770.780.67-0.92
ChineseHCCHLA-DQrs92753191.511.38-1.66[14]
STAT4*rs7574865