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World J Gastroenterol. Sep 7, 2013; 19(33): 5395-5401
Published online Sep 7, 2013. doi: 10.3748/wjg.v19.i33.5395
Published online Sep 7, 2013. doi: 10.3748/wjg.v19.i33.5395
Table 1 Single nucleotide polymorphisms within human leukocyte antigen loci associated with outcomes of hepatitis B virus infection
Ethnic group | Outcome | HLA locus | SNP | Odds | 95%CI | HLA haplotype | Odds | Ref. |
Japanese | Chronic infection | HLA-DPA1 | rs3077 | 0.56 | 0.51-0.61 | [7] | ||
HLA-DPB1 | rs9277535 | 0.57 | 0.52-0.62 | |||||
DPA1*0202-DPB1*0501 | 1.45 | |||||||
DPA1*0202-DPB1*0301 | 2.31 | |||||||
DPA1*0103-DPB1*0402 | 0.52 | |||||||
DPA1*0103-DPB1*0401 | 0.57 | |||||||
Japanese | Chronic infection | HLA-DQ | rs2856718 | 1.43 | 1.33-1.54 | [8] | ||
rs7453920 | 1.66 | 1.49-1.85 | ||||||
DQA1*0102-DQB1*0303 | 19.3 | |||||||
DQA1*0301-DQB1*0601 | 5.02 | |||||||
DQA1*0102-DQB1*0604 | 0.16 | |||||||
DQA1*0101-DQB1*0501 | 0.39 | |||||||
Chinese | Chronic infection | HLA-DPA1 | rs2395309 | 0.71 | 0.59-0.86 | [9] | ||
HLA-DPA1 | rs3077 | 0.64 | 0.53-0.78 | |||||
HLA-DPA1 | rs2301220 | 0.67 | 0.56-0.81 | |||||
HLA-DPA1 | rs9277341 | 1.77 | 1.39-2.25 | |||||
HLA-DPB1 | rs3135021 | 0.78 | 0.64-0.94 | |||||
HLA-DPB1 | rs9277535 | 0.56 | 0.47-0.68 | |||||
HLA-DPB1 | rs10484569 | 1.60 | 1.33-1.93 | |||||
HLA-DPB1 | rs3128917 | 1.91 | 1.59-2.30 | |||||
HLA-DPB1 | rs2281388 | 1.66 | 1.38-2.01 | |||||
HLA-DPB1 | rs3117222 | 0.51 | 0.42-0.61 | |||||
HLA-DPB1 | rs9380343 | 0.61 | 0.50-0.73 | |||||
Indonesian | Vaccine response | HLA-DR | rs3135363 | 1.59 | 1.45-1.73 | [10] | ||
HLA-DPB1 | rs9277535 | 0.82 | 0.71-0.96 | |||||
HLA-III | rs9267665 | 2.13 | 1.82-2.49 | |||||
Chinese | HCC | HLA-DQA1/DRB1 | rs9272105 | 1.28 | 1.22-1.35 | [11] | ||
GRIK1* | rs455804 | 0.84 | 0.80-0.89 | |||||
Japanese, Korean | Chronic infection | HLA-DPA1 | rs3077 | 0.46 | 0.39-0.54 | [12] | ||
HLA-DPB1 | rs9277542 | 0.50 | 0.43-0.60 | |||||
Chinese | Chronic infection | HLA-DPB1 | rs9277535 | 0.60 | 0.51-0.70 | [13] | ||
HLA-DPA1 | rs3077 | 0.81 | 0.75-0.95 | |||||
HLA-DQ | rs7453920 | 0.60 | 0.49-0.73 | |||||
HLA-DQ | rs2856718 | 0.75 | 0.64-0.89 | |||||
HCC | HLA-DQ | rs2856718 | 0.70 | 0.59-0.83 | ||||
HLA-DPA1 | rs3077 | 0.78 | 0.67-0.92 | |||||
Chinese | HCC | HLA-DQ | rs9275319 | 1.51 | 1.38-1.66 | [14] | ||
STAT4* | rs7574865 |
- Citation: Tamori A, Kawada N. HLA class II associated with outcomes of hepatitis B and C infections. World J Gastroenterol 2013; 19(33): 5395-5401
- URL: https://www.wjgnet.com/1007-9327/full/v19/i33/5395.htm
- DOI: https://dx.doi.org/10.3748/wjg.v19.i33.5395