Systematic review and meta-analysis of laparoscopy-assisted and open total gastrectomy for gastric cancer

Table 1 Characteristics of included studies

Ref.	Nation	Study type	Study period	Sample size		Stage	Level of lymphadenectomy	Follow-up (mo)		Level of evidence
				LATG	OTG			LATG	OTG
Kim et al[30]	South Korea	Retro	2004-2006	27	33	EC + AC	D1 + α/β, D2	NR	NR	2b
Mochiki et al[31]	Japan	Retro	1999-2007	20	18	EC + AC	D1 + β	31 (3-60)	46 (13-60)	2b
Sakuramoto et al[32]	Japan	Retro	2003-2007	30	44	EC + AC	D1 + β, D2	30		4
Kawamura et al[33]	Japan	Retro	2003-2008	46	35	EC	D2	NR	NR	4
Du et al[34]	China	Retro	2005-2009	82	94	AC	D2	25 (2-44)		2b
Kim et al[35]	South Korea	Pros	2009-2010	63	127	EC + AC	D2	NR	NR	2b
Kunisaki et al[36]	Japan	Pros	2002-2008	27	30	EC + AC	D1 + β	NR	NR	3b
Eom et al[37]	Korea	Retro	2003-2008	100	348	EC + AC	D2	52.6 (0.3-95.7)		4
Guan et al[38]	China	Pros	2007-2010	41	56	EC + AC	D2	NR	NR	3b

Retro: Retrospective observational study; Pros: Prospective observational study; EC: Early gastric cancer; AC: Advanced gastric cancer; NR: Not reported; LATG: Laparoscopy-assisted total gastrectomy; OTG: Open total gastrectomy.