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World J Gastroenterol. Aug 28, 2013; 19(32): 5295-5301
Published online Aug 28, 2013. doi: 10.3748/wjg.v19.i32.5295
Published online Aug 28, 2013. doi: 10.3748/wjg.v19.i32.5295
Table 2 Total numbers and frequencies of binucleated cells with micronucleus, nucleoplasmic bridges and nuclear buds scored using the cytokinesis-blocked micronucleus cytome assay in phytohemagglutinin-stimulated lymphocytes from patients with non-alcoholic steatohepatitis and the control subjects
ID | Age (yr) | Sex | No. of MN in BN cells1 | Distribution of BN cells with | No. of BN cells with NPBs | No. of BN cells with NBUDs | ||||
1MN | 2MN | 3MN | 4MN | 5MN | ||||||
Patients with non-alcoholic steatohepatitis | ||||||||||
1 | 45 | M | 19 | 15 | - | - | 1 | - | 25 | 19 |
2 | 60 | M | 24 | 19 | 1 | 1 | - | - | 46 | 11 |
3 | 50 | M | 33 | 24 | 1 | 1 | 2 | - | 33 | 22 |
4 | 66 | M | 41 | 39 | 1 | - | - | - | 20 | 22 |
5 | 22 | M | 8 | 8 | - | - | - | - | 32 | 17 |
6 | 43 | M | 33 | 29 | 2 | - | - | - | 25 | 14 |
7 | 36 | F | 14 | 14 | - | - | - | - | 21 | 17 |
8 | 51 | F | 9 | 9 | - | - | - | - | 16 | 10 |
9 | 35 | M | 21 | 16 | - | - | - | 1 | 25 | 14 |
10 | 42 | M | 11 | 11 | - | - | - | - | 12 | 15 |
11 | 30 | F | 28 | 24 | 2 | - | - | - | 50 | 20 |
12 | 22 | M | 11 | 7 | 2 | - | - | - | 17 | 15 |
13 | 31 | M | 12 | 10 | 1 | - | - | - | 21 | 16 |
14 | 41 | M | 15 | 13 | 1 | - | - | - | 18 | 25 |
15 | 33 | M | 10 | 10 | - | - | - | - | 30 | 10 |
16 | 44 | F | 22 | 17 | 1 | 1 | - | - | 58 | 21 |
17 | 47 | M | 20 | 13 | 2 | 1 | - | - | 40 | 17 |
18 | 20 | M | 25 | 16 | 1 | 1 | - | 1 | 14 | 10 |
19 | 22 | M | 24 | 20 | - | - | 1 | - | 32 | 8 |
20 | 46 | F | 37 | 27 | 2 | 2 | - | - | 25 | 10 |
21 | 68 | F | 36 | 26 | 5 | - | - | - | 63 | 28 |
22 | 48 | M | 17 | 15 | 1 | - | - | - | 28 | 6 |
23 | 60 | M | 22 | 18 | - | - | 1 | - | 36 | 19 |
24 | 45 | F | 24 | 20 | 2 | - | - | - | 25 | 14 |
25 | 41 | M | 24 | 19 | 1 | 1 | - | - | 20 | 10 |
The control subjects | ||||||||||
1 | 45 | M | 5 | 5 | - | - | - | 11 | 3 | |
2 | 60 | M | 8 | 6 | 1 | - | - | 10 | 5 | |
3 | 50 | M | 7 | 7 | - | - | - | 6 | 5 | |
4 | 66 | M | 11 | 9 | 1 | - | - | 12 | 6 | |
5 | 22 | M | 2 | 2 | - | - | - | 2 | 4 | |
6 | 43 | M | 6 | 4 | 1 | - | - | 1 | 4 | |
7 | 36 | F | 3 | 3 | - | - | - | 9 | 4 | |
8 | 51 | F | 9 | 5 | 2 | - | - | 5 | 3 | |
9 | 35 | M | 4 | 2 | 1 | - | - | 4 | 1 | |
10 | 42 | M | 6 | 6 | - | - | - | 7 | 5 | |
11 | 30 | F | 8 | 8 | - | - | - | 1 | 4 | |
12 | 22 | M | 2 | 2 | - | - | - | 8 | 4 | |
13 | 31 | M | 2 | 2 | - | - | - | 10 | 5 | |
14 | 41 | M | 7 | 5 | 1 | - | - | 16 | 8 | |
15 | 33 | M | 7 | 7 | - | - | - | 12 | 6 | |
16 | 44 | F | 11 | 8 | - | 1 | - | 5 | 6 | |
17 | 47 | M | 9 | 7 | 1 | - | - | 4 | 2 | |
18 | 20 | M | 1 | 1 | - | - | - | 8 | 4 | |
19 | 22 | M | 4 | 4 | - | - | - | 9 | 1 | |
20 | 46 | F | 11 | 7 | 2 | - | - | 8 | 3 | |
21 | 65 | F | 17 | 15 | 1 | - | - | 9 | 5 | |
22 | 48 | M | 12 | 10 | 1 | - | - | 14 | 6 | |
23 | 60 | M | 6 | 6 | - | - | - | 13 | 3 | |
24 | 45 | F | 11 | 9 | 1 | - | - | 5 | 3 | |
25 | 41 | M | 3 | 3 | - | - | - | 7 | 5 |
- Citation: Karaman H, Karaman A, Donmez-Altuntas H, Bitgen N, Hamurcu Z, Oguz A, Karakukcu C. Investigation of genome instability in patients with non-alcoholic steatohepatitis. World J Gastroenterol 2013; 19(32): 5295-5301
- URL: https://www.wjgnet.com/1007-9327/full/v19/i32/5295.htm
- DOI: https://dx.doi.org/10.3748/wjg.v19.i32.5295