Somatic molecular changes and histo-pathological features of colorectal cancer in Tunisia

doi:10.3748/wjg.v19.i32.5286

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 28, 2013; 19(32): 5286-5294
Published online Aug 28, 2013. doi: 10.3748/wjg.v19.i32.5286

Table 6 Comparison of mucin 5AC expression as a function of tumoral parameters

	MUC5AC expression (n = 15)	Absence of MUC5AC expression (n = 36)	P
MSI phenotype (n = 10)	46.70%	8.30%	0.0039¹
MMR expression loss (n = 10)	46.70%	8.30%	0.0039¹
TP53 mutations (n = 28)	40.00%	68.80%	NS
TP53 overexpression (n = 21)	33.30%	44.40%	NS
KRAS mutations (n = 16)	26.70%	33.30%	NS

¹Fisher exact test. NS: Not significant; MSI: Microsatellite instability; MUC: Mucin; MMR: Mismatch repair.

Citation: Aissi S, Buisine MP, Zerimech F, Kourda N, Moussa A, Manai M, Porchet N. Somatic molecular changes and histo-pathological features of colorectal cancer in Tunisia. World J Gastroenterol 2013; 19(32): 5286-5294
URL: https://www.wjgnet.com/1007-9327/full/v19/i32/5286.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i32.5286