Somatic molecular changes and histo-pathological features of colorectal cancer in Tunisia

doi:10.3748/wjg.v19.i32.5286

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 28, 2013; 19(32): 5286-5294
Published online Aug 28, 2013. doi: 10.3748/wjg.v19.i32.5286

Table 5 Comparison of TP53 somatic mutations as a function of tumoral parameters

	*Presence of TP53* mutations (n = 28)**	*Absence of TP53* mutations (n = 19)**	P
MSI	10.70%	36.80%	NS
MMR expression loss	10.70%	36.80%	NS
KRAS mutations	25.00%	47.40%	NS
TP53 surexpression	60.70%	21.10%	0.0090¹
MUC5AC surexpression	21.40%	47.40%	NS

¹Fisher exact test. NS: Not significant; MSI: Microsatellite instability; MUC: Mucin; MMR: Mismatch repair.

Citation: Aissi S, Buisine MP, Zerimech F, Kourda N, Moussa A, Manai M, Porchet N. Somatic molecular changes and histo-pathological features of colorectal cancer in Tunisia. World J Gastroenterol 2013; 19(32): 5286-5294
URL: https://www.wjgnet.com/1007-9327/full/v19/i32/5286.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i32.5286