Somatic molecular changes and histo-pathological features of colorectal cancer in Tunisia

doi:10.3748/wjg.v19.i32.5286

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 28, 2013; 19(32): 5286-5294
Published online Aug 28, 2013. doi: 10.3748/wjg.v19.i32.5286

Table 4 Comparison of the microsatellite instability phenotype as a function of tumoral parameters

	MSI-H tumors (n = 10)	MSS tumors (n = 41)	P
MMR expression	100.00%	0.00%	< 0.0001¹
KRAS mutations	40.00%	29.30%	NS
TP53 mutations	30.00%	67.60%	NS
TP53 surexpression	10.00%	48.80%	0.0335¹
MUC5AC surexpression	70.00%	19.50%	0.0039¹

¹Fisher exact test. NS: Not significant; MSI: Microsatellite instability; MUC: Mucin; MMR: Mismatch repair; MSS: Microsatellite stable.

Citation: Aissi S, Buisine MP, Zerimech F, Kourda N, Moussa A, Manai M, Porchet N. Somatic molecular changes and histo-pathological features of colorectal cancer in Tunisia. World J Gastroenterol 2013; 19(32): 5286-5294
URL: https://www.wjgnet.com/1007-9327/full/v19/i32/5286.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i32.5286