Rikkunshito improves globus sensation in patients with proton-pump inhibitor-refractory laryngopharyngeal reflux

Figure 2 Effects of rikkunshito alone and rikkunshito plus proton-pump inhibitor on gastric emptying in patients with proton-pump inhibitor-refractory laryngopharyngeal reflux. Each value represents the mean ± SD. ^aP < 0.05, significantly different from the number of markers at week 0 in the rikkunshito + proton-pump inhibitor (PPI) group (Wilcoxon signed-rank test). We found no significant difference between treatment groups after the 4-wk treatment period (Wilcoxon rank-sum test).