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World J Gastroenterol. Aug 14, 2013; 19(30): 4935-4943
Published online Aug 14, 2013. doi: 10.3748/wjg.v19.i30.4935
Published online Aug 14, 2013. doi: 10.3748/wjg.v19.i30.4935
Table 7 Genetic association between inflammatory bowel disease-phenotype and either newly discovered Claudin-2 promoter polymorphisms or a nonsynonymous coding polymorphisms in MORC4 was analyzed by performing case-control studies
rs62605981 (CLDN2) | rs72466477 (CLDN2) | rs6622126 (MORC4) | ||||
allelic OR (95%CI) | P value | allelic OR (95%CI) | P value | allelic OR(95%CI) | P value | |
IBD | 1.11 (0.71-1.73) | 0.659 | 1.23 (0.79-1.91) | 0.350 | 1.24 (0.91-1.70) | 0.179 |
CD | 0.83 (0.49-1.41) | 0.501 | 1.16 (0.68-2.00) | 0.584 | 1.61 (1.08-2.41) | 0.018 |
UC | 1.24 (0.69-2.26) | 0.463 | 1.19 (0.68-2.06) | 0.543 | 0.903 (0.61-1.33) | 0.606 |
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Citation: Söderman J, Norén E, Christiansson M, Bragde H, Thiébaut R, Hugot JP, Tysk C, O’Morain CA, Gassull M, Finkel Y, Colombel JF, Lémann M, Almer S. Analysis of single nucleotide polymorphisms in the region of
CLDN2-MORC4 in relation to inflammatory bowel disease. World J Gastroenterol 2013; 19(30): 4935-4943 - URL: https://www.wjgnet.com/1007-9327/full/v19/i30/4935.htm
- DOI: https://dx.doi.org/10.3748/wjg.v19.i30.4935