Thiopurines related malignancies in inflammatory bowel disease: Local experience in Granada, Spain

doi:10.3748/wjg.v19.i30.4877

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 14, 2013; 19(30): 4877-4886
Published online Aug 14, 2013. doi: 10.3748/wjg.v19.i30.4877

Table 3 Treatments n (%)

	Thiopurines (n = 429)	No thiopurines (n = 383)	P value
TPMT activity	283 (66)	-
Low	5 (1.8)	-
Intermediate	43 (15.2)	-
High	235 (83)	-
Azathioprine	341 (79.5)	-
Mercaptopurine	60 (14)	-
Azathioprine + Mercaptopurine	28 (6.5)	-
Infliximab	112 (26.1)	7 (1.8)	< 0.001
Adalimub	50 (11.7)	3 (0.8)	< 0.001
Other immunosuppressants	29 (6.8)	4 (1)	< 0.001

Patients (98.2%) treated with thiopurines have intermediate or high activity. Most of the patients treated with thiopurines take azathioprine. TPMT: Thiopurine S-methyltransferase.

Citation: Gómez-García M, Cabello-Tapia MJ, Sánchez-Capilla AD, Teresa-Galván JD, Redondo-Cerezo E. Thiopurines related malignancies in inflammatory bowel disease: Local experience in Granada, Spain. World J Gastroenterol 2013; 19(30): 4877-4886
URL: https://www.wjgnet.com/1007-9327/full/v19/i30/4877.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i30.4877