Helicobacter pylori tumor necrosis factor-&alpha; inducing protein promotes cytokine expression via nuclear factor-&kappa;B

doi:10.3748/wjg.v19.i3.399

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 21, 2013; 19(3): 399-403
Published online Jan 21, 2013. doi: 10.3748/wjg.v19.i3.399

Table 2 Cytokine levels in GES-1 and SGC7901 cells after interference with different concentrations of recombinant tumor necrosis factor-α inducing protein for 2 h

Groups	0	12.5μg/mL	25μg/mL	50μg/mL
GES-1 (IL-1β)	0.59 + 0.11	2.07 + 0.30^a	2.20 + 0.09^a	1.23 + 0.13^a
SGC-7901 (IL-1β)	0.36 + 0.01	2.07 + 0.10^a	1.22 + 0.03^a	1.02 + 0.04^a
GES-1 (IL-8)	0.39 + 0.08	0.84 + 0.11^a	0.75 + 0.09^a	0.61 + 0.15^a
SGC-7901 (IL-8)	0.78 + 0.09	2.53 + 0.50^a	1.50 + 0.16^a	1.41 + 0.14^a
GES-1 (TNF-α)	0.30 + 0.06	0.72 + 0.08^a	0.54 + 0.13^a	0.63 + 0.10^a
SGC-7901 (TNF-α)	0.26 + 0.18	1.41 + 0.10^a	0.62 + 0.07^a	0.62 + 0.02^a

^aP < 0.05 vs group 0. IL-1β: Interleukin-1β; TNF-α: Tumor necrosis factor-α.

Citation: Tang CL, Hao B, Zhang GX, Shi RH, Cheng WF. Helicobacter pylori tumor necrosis factor-α inducing protein promotes cytokine expression via nuclear factor-κB. World J Gastroenterol 2013; 19(3): 399-403
URL: https://www.wjgnet.com/1007-9327/full/v19/i3/399.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i3.399