Garcinia Cambogia attenuates diet-induced adiposity but exacerbates hepatic collagen accumulation and inflammation

Figure 3 Effects of Garcinia Cambogia supplementation on glucose tolerance and plasma adipocytokine levels in mice fed a high-fat diet for 16 wk. Data are expressed as the mean ± SE (n = 10). A: The intraperitoneal glucose tolerance test was performed on the 15^th week of Garcinia Cambogia (GC) supplementation in high-fat diet (HFD)-fed mice. Following a 12-h fast, the mice were injected intraperitoneally with glucose (0.5 g/kg body weight). Blood glucose was then measured via the tail vein at the indicated time [above: Blood glucose values; below: Areas under the curves (AUC)]; B, C: Plasma levels of leptin, resistin, monocyte chemoattractant protein-1 (MCP-1) and tumor necrosis factor-α (TNF-α) were assayed after 16 wk of GC supplementation in HFD-fed mice. HFD, mice fed a high-fat diet alone; HFD + GC, mice fed a high-fat diet containing GC (1%, w/w). ^aP < 0.05 vs control group.