Risk of sedation for diagnostic esophagogastroduodenoscopy in obstructive sleep apnea patients

Table 2 Procedural characteristics and adverse events in the obstructive sleep apnea and control groups

	OSA group (n = 31)	Control group (n = 65)	P value
EGD data
Duration of EGD (s)	261.4 ± 79.6	304.4 ± 154.2	0.074
Midazolam dosage (mg)	5.3 ± 0.9	4.5 ± 0.8	0.000
MOAA/S score (points, at 2 min)	2.5 ± 1.2	2.9 ± 1.0	0.146
Level of sedation for EGD			0.024
Moderate sedation	13 (41.9)	43 (66.2)
Deep sedation	18 (58.1)	22 (33.8)
Adverse events
Sedation failure	0 (0.0)	0 (0.0)	-
Paradoxical responses	4 (12.9)	4 (6.2)	0.268
Snoring or apnea	5 (16.1)	7 (10.8)	0.458
Hypoxia (SaO2 < 90%)	1 (3.2)	7 (10.8)	0.211
Hypotension	0 (0.0)	0 (0.0)	-
Other adverse events	0 (0.0)	0 (0.0)	-
Oxygen administration	1 (3.2)	1 (0.2)	0.588
Flumazenil administration	0 (0.0)	0 (0.0)	-

Data are expressed as absolute n (%) or mean ± SD. OSA: Obstructive sleep apnea; EGD: Esophagogastroduodenoscopy; MOAA/S: Modified Observer’s Assessment of Alertness/Sedation; SaO₂: Arterial oxygen saturation.