Retroperitoneal cavernous hemangioma resected by a pylorus preserving pancreaticoduodenectomy

Figure 4 Pathological analysis by hematoxylin and eosin staining and immunohistochemistry. A: A representative tissue section from the main region of the cavernous hemangioma [hematoxylin and eosin (HE), magnification × 200]; B: The loupe view demonstrates a portion of cavernous hemangioma infiltrating the pancreatic head (asterisk) and duodenal wall (HE). The scale represents 10 mm; C: Tumor invasion into the muscle layer of the duodenum (HE, magnification × 4); D: Tumor invasion into the pancreas head (HE, magnification × 1); E: Positive immunostaining for CD31 supports the diagnosis of hemangioma (magnification × 20); F: The lumen showed partial and weakly positive staining for podoplanin/D2-40 (magnification × 20).