Prediction of the severity of acute pancreatitis on admission by urinary trypsinogen activation peptide: A meta-analysis

Table 1 Characteristics of included prospective studies for urinary trypsinogen activation peptide as a predictor of severity of acute pancreatitis

Ref.	Year	Country	Sampling time after admission	Cut-off value (nmol/L)	Total (n)	Male/female (n)	Mild/severe (n)	Mean age: male/female (yr)	Etiology
Neoptolemos et al[32]	2000	Multicenter	On admission	35	172	87/85	137/35	52 (29-84)	Biliary 74, alcoholic 62, other 36
Liu et al[34]	2002	China	On admission	35	41	NA	29/12	NA	NA
Khan et al[33]	2002	United States	On admission	35	58	33/25	39/19	69 ± 19	Biliary 26, alcoholic 18, HTC 3, postoperative (including ERCP) 9, idiopathic 2
Lempinen et al[35]	2003	Finland	On admission	35	127	NA	98/29	NA	Biliary 24, alcoholic 74, other 29
Johnson et al[37]	2004	Multicenter	On admission	35	190	104/86	164/26	54 (42-70)	Biliary 70, alcohol 65, other 55
Huang et al[38]	2010	China	On admission	35	187	112/75	149/38	60.4 ± 6.7;	Biliary 139, alcoholic 19, other 29
								59.5 ± 8.1

ERCP: Endoscopic retrograde cholangiopancreatography; HTC: Hypercholesterolemic; NA: Not available.