Impact of being overweight on the surgical outcomes of patients with gastric cancer: A meta-analysis

Table 2 Summary statistics of pooled data comparing normal body mass index vs high body mass index for overall patients, patients receiving open gastrectomy and laparoscopic gastrectomy

Outcome variables	Studies	Pooled patients	Pooled RR or MD or HR	95%CI	Test for overall effect		Test for heterogeneity
					Z	P value	I2	P value
Overall patients
Operative time	9	5905	-29.14	-38.08, -20.21	6.39	< 0.00001	70%	0.0008
Retrieved lymph nodes	6	4612	1.69	0.75, 2.62	3.55	0.0004	9%	0.36
Blood loss	5	2096	-194.58	-314.21, -74.95	3.19	0.001	86%	< 0.00001
Morbidity	17	17514	0.75	0.66, 0.85	4.48	< 0.00001	58%	0.001
Anastomotic leak	19	12367	0.59	0.42, 0.82	3.07	0.002	34%	0.07
Pancreatic fistula	8	2959	0.46	0.34, 0.63	4.90	< 0.00001	16%	0.3
Mortality	13	16590	0.86	0.58, 1.29	0.71	0.48	0%	0.76
Postoperative hospital stay	6	4552	-5.83	-13.44, 1.78	1.5	0.19	98%	< 0.00001
Cancer-specific survival	5	12321	1.14	1.07, 1.20	4.21	< 0.0001	85%	< 0.0001
Patients receiving open gastrectomy
Operative time	7	2179	-25.24	-33.53, -16.95	5.97	< 0.00001	53%	0.05
Retrieved lymph nodes	6	2838	3.81	-0.34, 7.96	1.8	0.07	91%	< 0.00001
Blood loss	5	1708	-212.93	-301.04, -124.82	4.74	< 0.00001	74%	0.004
Morbidity	11	12510	0.78	0.66, 0.94	2.68	0.007	64%	0.002
Anastomotic leak	14	7320	0.58	0.38, 0.89	2.51	0.01	37%	0.08
Pancreatic fistula	6	2470	0.46	0.38, 0.67	4.03	< 0.0001	37%	0.16
Mortality	10	12763	1.17	0.69, 2.01	0.58	0.56	0%	0.83
Postoperative hospital stay	4	1339	-2.04	-6.00, 1.91	1.01	0.31	80%	0.002
Cancer-specific survival	4	12180	1.14	1.07, 1.20	4.23	< 0.0001	89%	< 0.00001
Patients receiving laparoscopic gastrectomy
Operative time	4	1845	-15.06	-17.41, -12.70	12.52	< 0.00001	0%	0.52
Retrieved lymph nodes	3	1746	2.11	1.35, 2.88	5.39	< 0.00001	0%	0.61
Blood loss	3	360	-47.83	-68.12,-27.53	4.62	< 0.00001	47%	0.15
Morbidity	6	3151	0.48	0.29, 0.79	2.91	0.004	67%	0.009
Anastomotic leak	6	3194	0.83	0.42, 1.65	0.53	0.6	32%	0.2
Pancreatic fistula	3	489	0.3	0.08, 1.20	1.7	0.09	10%	0.33
Mortality	3	1833	0.4	0.12, 1.30	1.53	0.13	0%	0.41
Postoperative hospital stay	3	1833	0.17	-0.80, 1.15	0.35	0.73	34%	0.22
Cancer-specific survival	1	141	1.65	0.13, 20.70	0.39	0.7	Not applicable	Not applicable