Phytoestrogens/insoluble fibers and colonic estrogen receptor β: Randomized, double-blind, placebo-controlled study

Figure 2 Colocalization estrogen receptor-β receptor and caspase-3. A: Nuclear estrogen receptor (ER)-β expression (red signal); B: Nuclear caspase-3 expression (green signal); C: Nuclear contrast with TOPRO-3 (blue signal); D: merge of the three signals. Both molecules are localized in the upper third of the crypts (Confocal microscope × 400).