Transplantation vs resection for hepatocellular carcinoma with compensated liver function after downstaging therapy

Table 2 Baseline demographic and tumor characteristics in the two groups

	LT group (n = 31)	LR group (n = 35)	P value
Age (yr)	43.0 ± 8.2	45.5 ± 8.1	0.212
Gender (male:female)	20:11	20:15	0.544
Weight (kg)	68.6 ± 7.8	65.8 ± 10.6	0.241
Height (cm)	166.9 ± 8.6	164.6 ± 9.3	0.302
BMI (kg/m2)	22.8 ± 1.8	23.2 ± 2.4	0.404
Underlying liver disease			0.901
HBV	29	33
HCV	1	1
HBV and HCV	1	1
MELD score	8.6 ± 3.8	8.7 ± 4.7	0.866
Child score			0.617
A (5-6)	20	23
B (7-9)	11	12
C (≥ 10)	0	0
Serum creatinine (μmol/L)	71.3 ± 24.1	64.3 ± 20.9	0.212
Active lesion number (Pre-/Post-downstage)			0.672/0.721
One target	13/16	15/19
Two targets	10/9	14/11
Three targets	8/6	6/5
Total diameter of the tumors (cm)	6.8 ± 2.1/ 4.5 ± 1.7	6.7 ± 2.3/4.1 ± 1.9	0.786/0.376
AFP level (ng/mL)
Pre-downstage	1425.4 ± 1512.6	1332.9 ± 1122.5	0.777
Post-downstage	218.0 ± 244.0	248.6 ± 267.6	0.631
Tumor differentiation			0.960
Well	16	19
Moderate	7	6
Poor	8	10
Ishak score	4.6 ± 1.5	3.9 ± 1.3	0.069

LT: Liver transplantation; LR: Liver resection; HBV: Hepatitis B virus; HCV: Heptatitis C virus; AFP: Alpha-fetoprotein; BMI: Body mass index.