Phytoestrogens/insoluble fibers and colonic estrogen receptor β: Randomized, double-blind, placebo-controlled study

Table 4 Estrogen receptor-β and estrogen receptor-α, apoptosis and mitosis in non-recurrent patients

Non- recurrent	ER-βprotein	ER-βmRNA	ER-βLI	ER-βprotein	ER-βmRNA	ER-βLI	TUNEL LI	Caspase-3 LI	Ki-67 LI
ADI (median)	0.805	2.278	47.533	0.423	0.295	15.333	43.777	39.444	55.33
SD	0.131	1.192	15.472	0.062	0.26	9.76	17.243	15.63	20.41
PL (median)	0.773	1.105	34.875	0.532	0.159	16.750	31.375	29.53	45.31
SD	0.13	1.07	16.67	0.11	0.32	8.86	12.93	9.13	11.29

¹P = 0.04,

²P = 0.02,

³P = 0.05 vs placebo group. LI: Labeling index; ER: Estrogen receptor; TUNEL: Terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling; ADI: Active dietary intervention.