Polydatin attenuated food allergy via store-operated calcium channels in mast cell

Figure 4 Polydatin suppressed interleukin-4 release and immunoglobulin E production in ovalbumin-allergic rats. A: Body weight of rats on day 48 [left panel, before polydatin (PD) treatment] or day 52 (right panel, after PD treatment) are shown; B: The cytokine levels in rat small intestine tissue or peritoneal lavage solution were analyzed by enzyme-linked immunosorbent assay; C: Statistical analysis of ovalbumin (OVA)-specific immunoglobulin E (IgE) in serum, which were collected from allergic rats administered with or without PD. n = 8. ^aP < 0.05, ^bP < 0.01 vs phosphate-buffered saline (PBS) group; ^cP < 0.05, ^dP < 0.01 vs OVA group.