Differential mucin phenotypes and their significance in a variation of colorectal carcinoma

Table 2 Expression levels of the mucin core proteins in the adenoma carcinoma sequence

	Histology		MUC2			MUC5AC
No. of patient	Adenoma	Carcinoma	Adenoma	Carcinoma	P value1	Adenoma	Carcinoma	P value1
208	TV	WMDA	4	3	ND	4	1	ND
225	T	WMDA	4	4		3	2
237	TV	WMDA	4	4		2	4
243	TV	WMDA	4	4		4	4
84	TV	PDA	4	2	0.016	4	0	0.042
86	TV	PDA	4	0		1	0
87	TV	PDA	4	0		0	0
102	TV	PDA	4	0		4	0
116	T	PDA	2	0		2	0
138	T	PDA	4	0		3	0
148	T	PDA	3	0		0	0
15	TV	MUA	4	4	0.063	3	0	0.016
36	TV	MUA	4	4		3	3
37	TV	MUA	4	4		0	0
51	TV	MUA	4	4		3	3
131	T	MUA	4	2		3	1
148	TV	MUA	4	2		4	0
151	TV	MUA	4	3		3	1
155	TV	MUA	4	4		4	2
175	TV	MUA	4	4		4	2
191	TV	MUA	4	3		3	0

¹Wilcoxon signed-rank test. MUC: Mucin; T: Tubular adenoma; TV: Tubulovillous adenoma; WMDA: Well-to-moderately differentiated adenocarcinoma; PDA: Poorly differentiated adenocarcinoma; MUA: Mucinous adenocarcinoma; ND: Not determined.