Active treatments are a rational approach for hepatocellular carcinoma in elderly patients

Figure 1 Age distribution in different periods and the survival of patients with hepatocellular carcinoma. A: The age of patients who were admitted for the management of hepatocellular carcinoma was plotted for each 5-year interval since 1986: the median ages were significantly different among the different periods (P < 0.0001); B: The overall survival of 740 patients in five age groups who have already died or have been followed for longer than 1 year was calculated on the basis of Kaplan-Meier survival fractions: the median survival time of all cases was 1094 d; C: Overall survival was compared among the different age groups after compensation for background characteristics using a Cox proportional hazard model and was significantly different among age groups (P = 0.020). The solid black and dotted lines are the survival curves of the 80 years of age or older and 70-79 years of age groups, respectively. The other lines are 60-69 years of age, 50-59 years of age and 49 years of age or younger groups, indicated in colors ranging from dark to pale. ^bP < 0.01. The horizontal bars (A) indicate the median and interquartile range. The dotted horizontal lines (B and C) indicate a position of 50% survival.