Glycyrrhizic acid attenuates CCl4-induced hepatocyte apoptosis in rats via a p53-mediated pathway

Figure 1 Histological examination of liver by hematoxylin and eosin and Sirius red staining. A: Histological examination. Rats were treated with carbon tetrachloride (CCl₄) and/or glycyrrhizic acid (GA). Liver tissue sections were stained with hematoxylin and eosin or Sirius red (original magnification, × 100); B: Quantitative analysis of liver fibrosis by Sirius red staining. Results are represented as fibrotic area (%), which signifies the proportion of area stained red/area of total area-vascular lumen. Values are mean ± SD. ^aP < 0.05 vs CCl₄.