Glycyrrhizic acid attenuates CCl4-induced hepatocyte apoptosis in rats via a p53-mediated pathway

doi:10.3748/wjg.v19.i24.3781

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 28, 2013; 19(24): 3781-3791
Published online Jun 28, 2013. doi: 10.3748/wjg.v19.i24.3781

Table 1 Effect of glycyrrhizic acid on plasma alanine aminotransferase and aspartate aminotransferase activity in CCl₄-induced rats

Group	ALT (U/L)	AST (U/L)
Control	42.4 ± 6.0	70.2 ± 2.3
CCl₄	526.7 ± 57.2	640 ± 33.7
GA	342 ± 44.8^a	462.8 ± 30.6^a

^aP < 0.05 vs the carbon tetrachloride (CCl₄) group. GA: Glycyrrhizic acid; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase.

Citation: Guo XL, Liang B, Wang XW, Fan FG, Jin J, Lan R, Yang JH, Wang XC, Jin L, Cao Q. Glycyrrhizic acid attenuates CCl4-induced hepatocyte apoptosis in rats via a p53-mediated pathway. World J Gastroenterol 2013; 19(24): 3781-3791
URL: https://www.wjgnet.com/1007-9327/full/v19/i24/3781.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i24.3781