Small-bowel capsule endoscopy: A ten-point contemporary review

Table 8 Studies looking at the clinical validity of QuickView, feature of capsule endoscopy reading software, in small-bowel capsule endoscopy

Ref.	QuickView sampling rate	QuickView reading frame mode/reading speed (fps)	Average reading time (mean)	Comparison with/reading frame mode/reading speed used (fps)	Rapid®Reader version	Reviewers	Cases					QuickView		Lesions missed
							Total	OGIB	CD	Polyposis	Other	Sensitivity (%)	Specificity (%)
Ponferrada et al[100]	NS	25, 15, 5	NS	Conventional/NS/15, 15, 5		2	57	37	8	N/A	12	96.5 (5 fps)	NS	NS
Schmelkin[104]	NS	NS	NS	NS	4.0	1	47	47	N/A	N/A	N/A	100	100	N/A
Appalaneni et al[105]	NS	Single frame, 25	3 min	NS	NS	2	50	NS	NS	NS	NS	NS	NS	2
Westerhof et al[106]	High (17)	NS	4.4 min (median)	Conventional/dual view/18	4.0	2	100	56	30	2	12	NS	NS	13
Shiotani et al[107]	High (17)	Single, 6	17.9 min	NS	5.0	3	44	NS	NS	NS	14	NS	NS	10
Hosoe et al[108]	Normal	NS	NS	NS	5.0	3	45	NS	NS	NS	14	NS	NS	NS
Saurin et al[109]	NS	NS	11.6 min	Conventional/NS/NS	5.0	12	106	106	N/A	N/A	N/A	89.2	Jul-84	8
Shiotani et al[110]	5, 15, 25, 35	Single, NS	NS	NS	6.5	4	87	NS	NS	NS	NS	NS	NS	NS
Koulaouzidis et al[111]	35	Dual view (WL + BM)	475 s (QuickView WL)	Conventional/single or dual view/12-20	7.0	1	200	106	81	4	9	92.3 (QVWL P1 + P2)	96.3 (QVWL P1 + P2)
		18	450 s (QuickView BM)									91 (QVBM P1+P2)	96 (QVBM P1 + P2)
Kyriakos et al[112]	NS	NS, 3	16.3 min (6.7)	Conventional/NS/NS	5.0	2	100	55	22	3	20	NS	NS	12

NS: Not stated; NA: Not applicable; fps: Frames per second; QVWL; QuickView with white light; QVBM: QuickView with blue mode; OGIB: Obscure gastrointestinal bleeding; CD: Crohn’s disease; P1, P2: Classification as per probability of bleeding.