Aberrant glycosylation of the anti-Thomsen-Friedenreich glycotope immunoglobulin G in gastric cancer patients

Figure 5 Binding of lectins to Thomsen-Friedenreich glycotope-specific IgG and the survival of patients with stomach cancer. The probability of survival (Kaplan-Meier method) of stomach cancer patients in relation to lectin binding to Thomsen-Friedenreich glycotope (TF)-specific IgG. A: Concanavalin A (ConA) lectin binding of all cancer patients; B: Aleuria aurantia lectin (AAL) binding in all cancer patients; C: Sambucus nigra agglutinin (SNA) binding in all cancer patients; D: ConA binding in patients with stage 3-4 cancer; E: AAL binding in patients with stage 3-4 cancer; F: SNA binding of patients with stage 3-4 cancer. Patient lectin index values, which were either lower, equal to (dashed line) or higher (solid line) than the cut-off are compared. The cut-off levels were calculated using time-dependent receiver operator characteristic curve analysis.