Gastric precancerous lesions are associated with gene variants in Helicobacter pylori-susceptible ethnic Malays

Table 1 Single nucleotide polymorphisms associated with atrophic gastritis among Malays with Helicobacter pylori

rs ID	Chromosome	Gene	Minor allele	Allele frequency		χ2	HWE
				Cases	Control	P-value1	P-value
rs2614074	8 p21.1	PNOC	B	0.409	0.062	0.008	0.983
rs10504944	8 q22.1	GDF6	A	0.5	0	0.034	0.516
rs9315542	13 q13.3	UFM1	B	0.409	0.064	0.007	0.994
rs4943552	13 q13.3	UFM1	A	0.318	0.075	0.040	0.815
rs489977	18 q12.3	KC6	A	0.181	0	0.064	0.752

rs ID: The unique ID for the identified single nucleotide polymorphisms; HWE: Hardy-Weinberg Equilibrium.

¹All markers were run using the FAMHAP (Haplotype Association Analysis) program. The P value represents the simulated overall significance for the particular marker corrected for multiple testing and P < 0.05 was considered statistically significant.