Human liver tissue metabolic profiling research on hepatitis B virus-related hepatocellular carcinoma

Figure 5 Selecting process of characteristic metabolites. A: Orthogonal partial least squares discriminant analysis model of the central tumor tissue group and distant tissue group, each point in the figure represents a sample; B: Variable importance (VIP) diagram with confidence interval (green bars were excluded metabolites, the others were target metabolites); C: Coefficient plot of included variants in the VIP diagram (variants marked by arrows were excluded metabolites); D: S-plot of selected ions passed last two steps of filtering (points marked by red frame represent characteristic metabolites). Distant: Distant tissue group; Central: Central tumor tissue group.