Psychometrics of chronic liver disease questionnaire in Chinese chronic hepatitis B patients

Table 6 Sensitivity of the chronic liver disease questionnaire in different alanine aminotransferase results after stratifying the disease

Scales	CHB with ALT test (n = 311)				CHB-related cirrhosis with ALT test (n = 64)
	Total score	Normal (n = 170)	Abnormal (n = 141)	ES	Total score	Normal (n = 29)	Abnormal (n = 35)	ES
Abdominal symptoms	5.59 ± 1.08	5.73 ± 1.04	5.41 ± 1.11	0.301b	5.34 ± 1.16	5.51 ± 1.17	5.20 ± 1.14	0.271
Fatigue	4.81 ± 1.08	4.88 ± 1.09	4.72 ± 1.08	0.15	4.61 ± 1.13	4.75 ± 1.21	4.49 ± 1.06	0.231
Systemic symptoms	5.54 ± 0.83	5.62 ± 0.82	5.44 ± 0.84	0.221	5.17 ± 0.83	5.24 ± 0.83	5.11 ± 0.84	0.16
Activity	5.70 ± 1.03	5.76 ± 1.00	5.62 ± 1.06	0.14	4.94 ± 1.21	5.09 ± 1.30	4.81 ± 1.14	0.231
Emotional function	4.85 ± 1.13	4.94 ± 1.16	4.75 ± 1.09	0.17	4.77 ± 1.06	4.85 ± 1.14	4.71 ± 1.00	0.13
Worry	5.02 ± 1.23	5.10 ± 1.23	4.93 ± 1.23	0.14	4.98 ± 1.20	4.94 ± 1.31	5.01 ± 1.12	-0.06
Overall	5.25 ± 0.84	5.34 ± 0.83	5.15 ± 0.84	0.231a	4.97 ± 0.81	5.06 ± 0.88	4.89 ± 0.74	0.211

¹The effect size (ES) ≥ 0.20. Effect size was calculated as the difference between alanine aminotransferase (ALT) normal and abnormal group mean scores divided by standard deviation of the total score. Significant difference by independent sample t-test between ALT normal and abnormal groups:

^aP < 0.05,

^bP < 0.01.