Effect of endogenous insulin-like growth factor and stem cell factor on diabetic colonic dysmotility

Figure 3 Effects of insulin-like growth factor-1 siRNA on stem cell factor expression. A: Effects on stem cell factor (SCF) mRNA levels in colonic smooth muscle cells (SMCs) 72 h after of transfection with insulin-like growth factor-1 (IGF-1) siRNA (Each bar represents the mean ± SE of 3 independent experiments). ^aP < 0.05, ^bP < 0.01 vs controls; ^cP < 0.05, ^dP < 0.01 vs negative controls; B: SCF protein expression in SMCs after IGF-1 knockdown for 72 h (figure is representative of 3 experiments). α-Tubulin was used as a loading control.