Treatment of hepatitis C in compensated cirrhotic patients is equally effective before and after liver transplantation

Table 1 Adverse events classification according to Common Terminology Criteria for Adverse Events v3.0

Adverse event	Grade 1	Grade 2	Grade 3	Grade 4	Grade 5
Anemia	Hb < LLN-10.0 g/dL	Hb 10.0-8.0 g/dL	Hb < 8.0-6.5 g/dL	Hb < 6.5 g/dL	Death
Neutropenia	PMN	PMN	PMN	PMN	Death
	< LLN-1.5 × 109/L	< 1.5-1.0 × 109/L	< 1.0-0.5 × 109/L	< 0.5 × 109/L
Intolerance:
Fatigue	Mild fatigue over baseline	Moderate or causing difficulty performing some ADL	Severe fatigue interfering with ADL	Disabling
Flu-like symptoms	Symptoms present but not interfering with function	Moderate or causing difficulty performing some ADL	Severe symptoms interfering with ADL	Disabling	Death
Depression	Mild mood alteration not interfering with function	Moderate mood alteration interfering with function, but not interfering with ADL; medication indicated	Severe mood alteration interfering with ADL	Suicidal ideation; danger to self or others	Death

ADL: Activities of daily living; PMN: Polymorphonuclear neutrophil.