Review
Copyright ©2013 Baishideng Publishing Group Co.
World J Gastroenterol. Jun 7, 2013; 19(21): 3199-3206
Published online Jun 7, 2013. doi: 10.3748/wjg.v19.i21.3199
Table 5 Interleukin-28B polymorphism in sofosbuvir and ABT-450 era
GroupStatus before treatmentIL-28B CC (n)IL-28B CT (n)IL-28B TT (n)SVR rate
Sofosbuvir
1Untreated541100%
2Untreated441100%
3Untreated442100%
4Untreated452100%
5Untreated26260%
6Untreated361100%
7No response to prior therapy25310%
8Untreated1112284%
ABT-450
1Untreated10/97/72/295%
2Untreated5/47/72/293%
3No or partial response to prior therapy0/012/65/247%