Nonalcoholic fatty liver disease and microvascular complications in type 2 diabetes

Figure 2 Prevalence of nonalcoholic fatty liver disease in T2DM with or without microangiopathy complications. A: Incidence of nonalcoholic fatty liver disease (NAFLD) negatively correlated with DN (r = -0.154, P < 0.05). This trend persisted even when patients were stratified by sex (r = -0.13 in men, r = -0.17 in women, both P < 0.05). Prevalence of NAFLD in T2DM with and without DN was 49.4% and 65.9%, respectively (^bP < 0.01 vs group without DN). Prevalence of NAFLD in men without DN was significantly higher than in patients with DN (63.3% and 49.3%, respectively, ^bP < 0.01 vs the group without DN). Prevalence of NAFLD in women without DN was significantly higher than in patients with DN (67.5% and 49.5%, respectively, ^bP < 0.01 vs the group without DN); B: Incidence of NAFLD negatively correlated with DPN (r = -0.086, P < 0.05). This trend persisted even when patients were stratified by sex (r = -0.095 in men, r = -0.084 in women, both P < 0.05). The general prevalence of NAFLD in T2DM with and without DPN was 57.2% and 65.6%, respectively (^bP < 0.01 vs the group without DPN). Prevalence of NAFLD in men without DPN was significantly higher than in patients with DPN (63.9% and 54.5%, respectively, ^aP < 0.05 vs the group without DPN). Prevalence of NAFLD in women without DPN was also significantly higher than that in patients with DPN (66.9% and 58.6%, respectively, ^aP < 0.05 vs the group without DPN); C: Incidence of NAFLD negatively correlated with DR (r = -0.114, P < 0.05). This trend persisted even when patients were stratified by sex (r = -0.176 in men, r = -0.076 in women, both P < 0.05). Prevalence of NAFLD in T2DM with and without DR was 54.9% and 66.1%, respectively (^bP < 0.01 vs the group without DR). Furthermore, the Prevalence of NAFLD in men without DR was significantly higher than that in patients with DR (66.9% and 49.5%, respectively, ^bP < 0.01 vs the group without DR). Prevalence of NAFLD in women without DR was also significantly higher than that in patients with DR (65.5% and 58.1%, respectively, ^aP < 0.05 vs the group without DR).