IL28B polymorphism and cytomegalovirus predict response to treatment in Egyptian HCV type 4 patients

Figure 2 Rate of sustained viral response in IL28B variants. Among 166 chronic hepatitis C (CHC) patients treated with combined interferon (IFN) and ribavirin therapy, 80 patients did not achieve a sustained viral response (SVR) while 86 patients achieved a SVR. Among the 14% (24) of CHC patients bearing the C/C allele, 67% (16 patients) achieved a SVR, while the other two genotypes C/T and TT were associated with lower SVR rates; 50% and 48%, respectively. Genotype CC was associated with response to IFN (P = 0.025). HCV: Hepatitis C virus.