Hyperglycemia is a significant prognostic factor of hepatocellular carcinoma after curative therapy

Figure 3 Kaplan-Meier curves showing a higher rate of second recurrence of hepatocellular carcinoma in diabetic patients with inadequate maintenance of blood glucose. A: The cumulative incidence of the second recurrence of hepatocellular carcinoma (HCC) was significantly higher in diabetic patients with inadequate maintenance of blood glucose (blood glucose ≥ 200 mg/dL solid line) than in the others (dotted line) (P = 0.002); B: The rate of second recurrence of HCC was significantly higher in diabetic patients with inadequate maintenance of blood glucose (solid line) than in diabetic patients with adequate maintenance of blood glucose (blood glucose < 200 mg/dL, broken line) or non-diabetic patients (dotted line) (P = 0.004). There was no significant difference in the rate of second recurrence of HCC between diabetic patients with adequate maintenance of blood glucose and non-diabetic patients.