Hyperglycemia is a significant prognostic factor of hepatocellular carcinoma after curative therapy

Figure 2 Diabetic patients with inadequate maintenance of blood glucose have higher rate of hepatocellular carcinoma recurrence after stratification by other risk factors. A: P = 0.006 for single hepatocellular carcinoma (HCC) nodule; B: P = 0.025 for multiple HCC nodules; C: P = 0.005 for AFP ≥ 100 ng/mL; D: P = 0.017 for α-fetoprotein (AFP) < 100 ng/mL. The cumulative incidence of the recurrence of HCC was significantly higher in diabetic patients with inadequate maintenance of blood glucose (solid line) than in the others (dotted line). after stratification by number of HCC nodules and by initial level of AFP.