Inositol-requiring enzyme 1α is required for gut development in Xenopus lavies embryos

Figure 2 Overexpression of inositol-requiring enzyme 1α affected neither mesoderm and endoderm formation nor gut development. A: Overexpression of inositol-requiring enzyme (IRE) 1α did not change the phenotype and the expression of Xbra and Xsox17α at stage 10.5; B: IRE1α mRNA injected embryos at tailbud stage were nearly normal; C: Embryos injected with IRE1α-GR mRNA did not display any defect until tadpole stage.