Intestinal injury can be reduced by intra-arterial postischemic perfusion with hypertonic saline

Figure 6 Representative samples of arterial blood pressure recordings in anesthetized rats subjected to intestinal ischemia-reperfusion in vivo. A: Thirty-minute superior mesenteric artery (SMA) occlusion followed by 30-min reperfusion (controls) resulted in a persistent blood pressure (BP) decrease over the entire reperfusion period; B: Thirty-minute SMA occlusion finalized by aortic clamping followed immediately by 5-min SMA perfusion with hypertonic saline (365 mOsm/L), with a subsequent 25-min reperfusion with blood, resulted in a transient drop with a rapid restoration of BP up to the initial values. HTS: Hypertonic saline.