Intestinal injury can be reduced by intra-arterial postischemic perfusion with hypertonic saline

Figure 5 Histologically defined scores in the ex vivo (A) and in vivo (B) experiments. A, B: In the sham group (no ischemia at all, A) slight injury only is evident, probably due to the prolonged perfusion in the extracorporeal environment. Sixty-minute ischemia followed by 30-min normotonic reperfusion (controls) resulted in a significant injurious effect, which, however, was substantially less expressed in the HTS^365mOsm but not in the HTS^415mOsm group. The analogous difference between the controls and the HTS^365mOsm group is apparent in the in vivo experiments (B). The data are expressed as mean ± SD; ^aP < 0.05 vs controls.