IL28B polymorphism and cytomegalovirus predict response to treatment in Egyptian HCV type 4 patients

doi:10.3748/wjg.v19.i2.290

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Jan 14, 2013 (publication date) through Apr 15, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 14, 2013; 19(2): 290-298
Published online Jan 14, 2013. doi: 10.3748/wjg.v19.i2.290

Table 2 Influence of cytomegalovirus infection on response rate to interferon combined therapy in chronic hepatitis C virus infected patients with IL28B CT genotype n (%)

HCV response to treatment (n =117)	IL 28B genotype (CT) +ve CMV patients (n = 45)	IL 28B genotype (CT) -ve CMV patients (n = 72)
NR (n = 59)	32 (71)	27 (38)
SVR (n = 58)	13 (29)	45 (62)

Reactivation of cytomegalovirus (CMV) was assessed by amplification of viral genome in all patients. Association of IL28B genotype CT and CMV emia with response to interferon based therapy is illustrated in this table. SVR: Sustained viral response; NR: Non-responder.

Citation: El Awady MK, Bader El Din NG, Tabll A, El Hosary Y, Abdel Aziz AO, El Khayat H, Salama M, Abdelhafez TH. IL28B polymorphism and cytomegalovirus predict response to treatment in Egyptian HCV type 4 patients. World J Gastroenterol 2013; 19(2): 290-298
URL: https://www.wjgnet.com/1007-9327/full/v19/i2/290.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i2.290