IL28B polymorphism and cytomegalovirus predict response to treatment in Egyptian HCV type 4 patients

Table 1 Statistical analyses of the different IL28B genotypes and alleles in non-responder and sustained viral response patients n (%)

	Non-responders (NR = 79)	Responders (SVR = 87)	Odds ratio	95%CI	P value
CC (n = 24)	8 (33.3)	16 (66.7)	4.575	1.376-7.846	0.025
CT (n = 117)	58 (49.6)	59 (50.4)	0.858	0.538-1.449	0.589
TT (n = 25)	13 (52)	12 (48)	0.978	0.758-1.759	0.464
C (n = 165)	74 (44.8)	91 (55.2)	1.636	0.773-3.465	0.198
T (n = 167)	84 (50.3)	83 (49.7)	0.798	0.598-1.349	0.604

Frequencies of genotypes and alleles at IL28B SNP were compared between SVR and NR patients. Genotype CC were associated with SVR (P = 0.025). SVR: Sustained viral response; NR: Non-responder.