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©2013 Baishideng Publishing Group Co.
World J Gastroenterol. Jan 14, 2013; 19(2): 265-273
Published online Jan 14, 2013. doi: 10.3748/wjg.v19.i2.265
Published online Jan 14, 2013. doi: 10.3748/wjg.v19.i2.265
Table 5 Comparison of clinical factors in one year outcomes of the two groups of active ulcerative colitis patients receiving intravenous corticosteroids after oral corticosteroid therapy failure
Good responders1(n = 25) | Poor responders2(n = 29) | P-value univariate | |
Gender (M/F) | 15/10 (60/40) | 16/13 (55/45) | 0.721 |
Age (yr) | 35 (16-78) | 39 (13-64) | 0.445 |
Disease duration (mo) | 30 (0-84) | 29 (0-120) | 0.325 |
≤ 24 | 14 (56) | 20 (69) | |
> 24 | 11 (44) | 9 (31) | |
First attack of UC | 9 (36) | 15 (51.7) | 0.248 |
Disease extent | 0.304 | ||
Proctitis | 1 (4) | 3 (10.3) | |
Left-sided colitis | 6 (24) | 11 (37.9) | |
Extensive colitis | 18 (72) | 15 (51.7) | |
Disease activity | |||
Full Mayo score (< 9/≥ 9) | 15/9 (62.5/37.5) | 11/14 (44/56) | 0.195 |
Partial Mayo score (< 6/≥ 6) | 9/16 (36/64) | 4/25 (13.8/86.2) | 0.057 |
Initial prednisolone dose (mg) | 0.785 | ||
≥ 30 and < 40 | 13 (52) | 14 (48.3) | |
≥ 40 | 12 (48) | 15 (51.7) | |
Duration of oral corticosteroid use (d) | 0.337 | ||
≤ 14 | 17 (68) | 16 (55.2) | |
> 14 | 8 (32) | 13 (44.8) | |
Concomitant medications | 0.771 | ||
Salicylates | 19 (76) | 23 (79.3) | |
Azathioprine | 6 (24) | 6 (20.7) | |
CRP (mg/dL) | |||
≤ 8 | 16 (64%) | 19 (65.5) | 0.907 |
> 8 | 9 (36%) | 10 (34.5) | |
ESR (mm/h) | 34.1 (4-81) | 46.3 (3-120) | 0.171 |
Hemoglobin (mg/dL) | |||
≤ 11 | 9 (36) | 8 (27.6) | 0.507 |
> 11 | 16 (64) | 21 (72.4) | |
Albumin (mg/dL) | 3.8 (2.7-4.7) | 3.57 (2.3-5.0) | 0.230 |
- Citation: Jeon HH, Lee HJ, Jang HW, Yoon JY, Jung YS, Park SJ, Hong SP, Kim TI, Kim WH, Cheon JH. Clinical outcomes and predictive factors in oral corticosteroid-refractory active ulcerative colitis. World J Gastroenterol 2013; 19(2): 265-273
- URL: https://www.wjgnet.com/1007-9327/full/v19/i2/265.htm
- DOI: https://dx.doi.org/10.3748/wjg.v19.i2.265