Gastrointestinal tuberculosis is not associated with proton pump inhibitors: A retrospective cohort study

Table 1 Clinical information of the patients who were endoscopically diagnosed with suspicious tuberculosis

	Gender/age	Group1	PPI duration before diagnosis (d)	Reason for endoscopy	Endoscopy findings	Pathology findings	Decision for analysis	Note
1	F/65	2	639	Diarrhea	Scar, cecum	No biopsy	Excluded
2	F/73	1	844	Abdominal pain	Scar, cecum	No biopsy	Excluded
3	F/65	2	1177	Routine check	Scar, cecum	No biopsy	Excluded
4	F/60	1	415	Routine check	Scar, terminal ileum	No biopsy	Excluded	Small bowel resection due to tuberculosis 20 years ago
5	F/64	1	616	Anemia	Scar, descending colon	No biopsy	Excluded
6	F/67	2	56	Abdominal pain	Scar, cecum	No biopsy	Excluded
7	F/55	2	87	Routine check	Scar, cecum	No biopsy	Excluded
8	F/82	2	523	Constipation	Scar, cecum	No biopsy	Excluded
9	F/58	1	65	Lower abdominal pain	Scar, cecum	No biopsy	Excluded
10	F/55	1	612	Routine check	Scar, cecum	No biopsy	Excluded
11	M/52	1	894	Blood-tinged stool	Scar, cecum	No biopsy	Excluded
12	F/61	2	29	Bloating	Scar, cecum	No biopsy	Excluded
13	F/72	1	125	Hematochezia	Ulcers, cecum	Chronic active colitis	Included
14	M/44	1	28	Anemia	Ulcers, cecum/ transverse colon	Non-caseating granuloma, negative PCR2	Included
15	F/63	2	55	Epigastric pain	Ulcer, gastric cardia	Non-caseating granuloma, positive PCR2	Included	Palpable right supraclavicular lymph node
16	M/49	1	7	Melena	Ulcers, terminal ileum	Chronic active ileitis	Excluded
17	M/41	1	574	Loose stool	Ulcers, cecum	Non-caseating granuloma, positive PCR2	Included
18	M/20	1	49	Lower abdominal pain	Ulcers, ileocecal valve	Chronic active colitis	Included
19	F/66	1	1	Melena	Ulcers, terminal ileum	Chronic active ileitis	Excluded
20	F/59	1	224	Lower abdominal pain	Ulcers, ileocecal valve	Chronic active colitis,	Included
21	F/46	1	28	Epigastric pain	Ulcers, mid-esophagus	Non-caseating granuloma, positive PCR2	Included

¹Patients with PPI treatment for three months or less as group 1, and patients with more-than-three-month PPI treatment as group 2;

²Polymerase chain reaction (PCR) for Mycobacterium tuberculosis. PPI: Proton pump inhibitor; M: Male; F: Female.