Overexpression of p42.3 promotes cell growth and tumorigenicity in hepatocellular carcinoma

Figure 4 Promotion of tumorigenesis by overexpression of p42. 3 shows statistical significance compared with the control in HepG2 cells. A: The tumor induced by HepG2-p42.3-1 and HepG2-p42.3-2 was much larger than that in the control; B: Over the course of 15 d, the tumor growth curve comparing HepG2-p42.3-1, HepG2-p42.3-2, and HepG2-vector cells revealed that p42.3-overexpressing cells grew faster (^bP < 0.01 vs HepG2-p42.3-1); C: Immunohistochemistry staining was performed in xenograft tissues from tumors. p42.3 protein was detectable in xenografts that were formed by injection of p42.3-overexpressing cells, but not in the tumors developed from HepG2-vector cells.