MAWBP and MAWD inhibit proliferation and invasion in gastric cancer

Figure 6 Combination of mitogen-activated protein kinase activator with WD40 repeats binding protein and mitogen-activated protein kinase activator with WD40 repeats inhibited the transforming growth factor-β pathway. A: The level of p-Smad3 was lowest in the mitogen-activated protein kinase activator (MAWD) with WD40 repeats binding protein (MAWBP)/D cotransfected group and highest in the vector group. p-Smad2 was also lower in the MAWBP/D group; B, C: Nuclear translocation capability of p-Smad3 in cotransfected cells was weakest that means the activity of transforming growth factor (TGF)-β pathway in co-expression group was inhibited. DAPI: 4’,6-diamidino-2-phenylindole.