Lipoic acid suppresses portal endotoxemia-induced steatohepatitis and pancreatic inflammation in rats

Figure 6 Effect of α-lipoic acid on plasma glucose and insulin levels. A hyperglycemic clamp technique was used to evaluate glucose-stimulated insulin secretion. A: Plasma glucose levels during the clamp period; B: Change in insulin levels during clamp period; C: The insulin level averages during the first phase (0-10 min) and the second phase (10-240 min) of the clamp period. Values are expressed as mean ± SE, n = 6 per group. ^aP < 0.05 vs C_PV; ^cP < 0.05 vs F_PV; ^eP < 0.05 vs F_PLPS. C: Regular diet; F: High-fructose enriched diet; LA: Lipoic acid; LPS: Lipopolysaccharides.